A team of researchers in Germany have come up with a method to prevent counterfeit materials being used to develop breast implants – through tomato DNA.
© Fraunhofer IAP
Dr. Joachim Storsberg shows a breast implant with a leaking gel filling.
A research team at the Fraunhofer Institute for Applied Polymer Research IAP have developed a way to use the DNA sequences from tomatoes as permanent markets to identify any implants that have been illegally tampered with.
Counterfeit medical products have become a major concern not only for manufacturers but also for consumers. Fake medical products tend to be inferior to the original and can put patients’ lives at risk.
In 2010, a French company blended unapproved silicones with its breast implants as a way to cut production costs. Illegal manipulation such as this can be very difficult to detect, requiring elaborate analyses to see if products have been tampered with.
To combat this, the team at the Fraunhofer Institute has developed a method which involves using tomato DNA as a way to positively identify implants.
“We isolated genomic DNA (gDNA) from tomato leaves and embedded it in the silicone matrix. We used approved siloxanes, which are building blocks for silicone products, to manufacture breast implants,” says Dr. Joachim Storsberg, a scientist at the Fraunhofer IAP in Potsdam and a witness in court cases centred on breast implants.
The team managed to prove that the extracted DNA’s temperature remained stable throughout pilot experiments. The method should be desirable to manufacturers: tomato DNA is inexpensive and is suitable as a counterfeit-proof market for many polymer-based implants.
“Breast implants are made up of components; that is, several silicone polymers that cross-link to form a gel. The components’ manufacturer now has the option of marking silicones with the encapsulated tomato DNA sequence during the production process. He alone knows the type and concentration of the DNA used. The components are marked first, and then sold to the implant manufacturer. The PCR method can detect if the manufacturer stretched components with inferior materials or used a lower concentration. “This works much like a paternity test,” explained Storsberg.
The procedure developed by Storsberg and his team – which includes Marina Volkert from Berlin’s Beuth University of Applied Sciences –has already been patented and is published in the Plastische Chirurgie journal.
