insulin
The company’s cyclic olefin copolymer (COC) has been used by Valeritas Holdings for its insulin delivery device.
The device is worn like a patch and offers patients with type 2 diabetes an alternative to having to take multiple daily shots of insulin.
The V-Go device is designed to simplify basal-bolus insulin therapy and helps adults contril their blood glucose levels. The device is fully disposable and is worn under the clothing.
Valeritas Holdings’ V-Go Wearable Insulin Delivery Device features an injection moulded cartridge made of Topas cyclic olefin copolymer (COC).
Topas’ COC material was selected due to its purity, drug compatibility, biocompatibility, and dimensional stability, according to Geoffrey Jenkins, executive vice president of manufacturing and research and development for Valeritas.
Jenkins said: “Topas COC fills an important role in the cartridge system of the V-Go insulin delivery device. We find it to be highly stable in contact with the drug and it has great optical clarity; moreover, it offers good injection moulding characteristics with excellent dimensional stability and minimal shrinkage.”
Valeritas reports that users switching from multiple daily insulin shots to V-Go significantly lowered their glucose levels and reduced their insulin use by as much as 44% per day.
Topas is highlighting its work with Valeritas Holdings at its booth (#666) in MD&M West this week, as well as Pharmapack (Stand B23).